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Indian pharma industry is very interested in the export of its pharmaceutics. Developing countries are an important market for Indian manufacturers because they produce high quality products at very competitive prices. But free trade is hampered by national and international patent rules. For a patent does not only constitute the sole right to produce a product but also to import it. Despite these barriers, India's drug exports exceeded in the year 2000 for the first time US$ 1, 5 billion. The success story of the pharmaceutical sector is part of a wider but less known "economic miracle": India achieved average rates of economic growth for the last 20 years of six percent annually and mexitil, because drug information.

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JAMA. 2003; 289: 712-718 Author Affiliations: Monash University, Melbourne, Victoria, Australia Dr Krum University of Wisconsin, Madison Dr Roecker University Hospital, Bern, Switzerland Dr Mohacsi Silesian School of Medicine, Katowice, Poland Dr Tendera University Health Network and Mt Sinai Hospital, Toronto, Ontario, Canada Dr Rouleau Royal Brompton Hospital, London, England Dr Coats Universitaets Klinikum Luebeck, Luebeck, Germany Dr Katus Stanford University Medical Center, Stanford, Calif Dr Fowler and the College of jama Physicians and Surgeons, Columbia University, New York, NY Dr Packer ; . The COPERNICUS Study Investigators and Coordinators are listed at the end of the article. Corresponding Author and Reprints: Henry Krum, MD, National Health and Medical Research Council Center of Clinical Research Excellence in Therapeutics, Dept of Medicine and Epidemiology and Preventive Medicine, Monash University, Alfred Hospital, Melbourne, Victoria, 3181 Australia, e-mail: henry.krum med.monash .au and mexiletine.
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ESTROGEN AND HEART RATE VARIABILITY 18. Kuo TBJ and Chan SHH. Continuous, on-line, real-time spectral analysis of arterial blood pressure using a personal computer. J Physiol Heart Circ Physiol 264: H2208H2213, 1993. 19. Kuo TBJ, Lin T, Yang CCH, Li CL, Chen CF, and Chou P. Effect of aging on gender differences in neural control of heart rate. J Physiol Heart Circ Physiol 277: H2233H2239, 1999. 20. Kuo TBJ and Yang CCH. Sexual dimorphism in the complexity of cardiac pacemaker activity. J Physiol Heart Circ Physiol 283: H1695H1702, 2002. 21. Kuttenn F and Gerson M. Hormone replacement therapy of menopause, heart and blood vessels. Arch Mal Coeur Vaiss 94: 685689, 2001. Malliani A, Pagani M, Lombardi F, and Cerutti S. Cardiovascular neural regulation explored in the frequency domain. Circulation 84: 482492, 1991. Mercuro G, Podda A, Pitzalis L, Zoncu S, Mascia M, Melis GB, and Rosano GMC. Evidence of a role of endogenous estrogen in the modulation of autonomic nervous system. J Cardiol 85: 787789, 2000. Pagani M, Montano N, Porta A, Malliani A, Abboud FM, Birkett C, and Somers VK. Relationship between spectral components of cardiovascular variabilities and direct measures of muscle sympathetic nerve activity in humans. Circulation 95: 14411448, 1997. Rosano GMC, Patrizi R, Leonardo F, Ponikowski P, Collins P, Sarrel PM, and Chierchia SL. Effect of estrogen replacement therapy on heart rate variability and heart rate in healthy postmenopausal women. J Cardiol 80: 815817, 1997. Ross RK, Paganini-Hill A, Mack TM, and Henderson BE. Cardiovascular benefits of estrogen replacement therapy. J Obstet Gynecol 160: 13011306, 1989. Saeki Y, Atogami F, Takahashi K, and Yoshizawa T. Reflex control of autonomic function induced by posture change during the menstrual cycle. J Auton Nerv Syst 66: 6974, 1997. Saleh MC, Connell BJ, and Saleh TM. Autonomic and cardiovascular reflex responses to central estrogen injection in ovariectomized female rats. Brain Res 879: 105114, 2000. Saleh TM, Cribb AE, and Connell BJ. Estrogen-induced recovery of autonomic function after middle cerebral artery oc. Depression is a chronic, disabling disorder & a the majority important worldwide public health problem and telmisartan.

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